Thursday, January 31, 2013

Everything You Wanted to Know About Facebook Groups

Click here to view the gallery: Facebook Groups 101

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Source: http://www.nccisp.org/?p=8321

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Wednesday, January 30, 2013

Kemba Walker & Michael Kidd-Gilchrist Selected To Play In The 2013 BBVA Rising Stars Challenge During NBA All-Star Weekend In Houston

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January 30, 2013 ? The NBA today announced that Charlotte Bobcats guard Kemba Walker and forward Michael Kidd-Gilchrist have been selected to play in the 2013 BBVA Rising Stars Challenge on Friday, February 15, during NBA All-Star Weekend in Houston.

?We are very excited that both Kemba and Michael were selected to participate in the Rising Stars Challenge this year,? said Bobcats President of Basketball Operations Rod Higgins. ?It speaks volumes that two of our last three first-round draft selections have been recognized as elite players from their class for their on-court performance.?

Walker, who is averaging 17.9 points, 5.8 assists, 3.5 rebounds and 1.9 steals in 35.0 minutes this season, is ranked among the league leaders in five statistical categories including steals (6th), steals per turnover (T-17th), assists (T-18th), scoring (19th) and minutes played (36th). His current streak of 15 consecutive games is the longest double-figure scoring streak of his career and longest by a Bobcats player since 2011.

He is joined by fellow second-year players Kenneth Faried (Denver), Kyrie Irving (Cleveland), Brandon Knight (Detroit), Kawhi Leonard (San Antonio), Chandler Parsons (Houston), Klay Thompson (Golden State), Tristan Thompson (Cleveland) and Nikola Vucevic (Orlando).

Kidd-Gilchrist, who is averaging 9.9 points and 6.0 rebounds in 26.7 minutes this season, is one of only nine rookies to have started at least 25 games this season. He is ranked in the Top 10 among all NBA Rookies in blocks (4th), rebounding (T-4th), steals (T-9th), assists (T-8th) and minutes played (8th). On Nov. 10 against Dallas and Dec. 19 against Phoenix, he posted 25 points and 12 rebounds, joining Miami?s LeBron James as the only two players in NBA history to tally at least 25 points and 12 rebounds in a game twice before their 20th birthday. He was also selected by the NBA as the Eastern Conference Rookie of the Month for November.

Joining Kidd-Gilchrist among the rookie selections are his college teammate Anthony Davis (New Orleans), Harrison Barnes (Golden State), Bradley Beal (Washington), Andre Drummond (Detroit), Damian Lillard (Portland), Alexey Shved (Minnesota), Dion Waiters and Tyler Zeller (Cleveland).

The BBVA Rising Stars Challenge -- televised live nationally on TNT at 9 p.m. ET and broadcast live on ESPN Radio, with live audio also available on NBA.com in multiple languages -- features two teams each consisting of nine rookies and sophomores mixed together, drafted from a pool selected by the NBA?s assistant coaches.

This marks the second straight year rookies and sophomores will be mixed together on teams. The BBVA Rising Stars Challenge Draft is scheduled for Thursday, Feb. 7, televised exclusively on TNT at 7 p.m. ET. TNT analysts Charles Barkley and Shaquille O?Neal will again serve as the general managers of TEAM CHUCK and TEAM SHAQ.

The last time the Bobcats were represented in the Rising Stars Challenge by both a rookie and sophomore player in the same game was during the 2006-07 season when Raymond Felton and Adam Morrison were selected.

-bobcats.com-

Tags: Charlotte Bobcats, Kemba Walker, Michael Kidd-Gilchrist, NBA

Source: http://www.sportspagemagazine.com/content/bb/mp-bb/ln-mp-bb/kemba-walker-michael-kidd-gilchrist-selected-to-pl.shtml?55641

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Ay caramba! Singapore's best Latin American restaurants - Food ...

Operating Hours: Various

It?s not quite Latin American fever that's hitting Singapore, but certainly the number of Latin American restaurants has been gradually on the increase over the past year or so. And we say ? hurrah to that!

From Brazilian, Mexican, to Argentinian, the older players have been joined by fresh young upstarts, infusing our dining scene with those sunny, laid back flavours.

So here we bring you our round up of our favourite Latin Amercian restaurants which we think you should say ?Ola!? to.

Brazil Churrasco

Dubbed the finest Brazilian steakhouse in Singapore, this place keeps true to the typical set up in a Brazilian steakhouse i.e. pay a set price (a very reasonable $45++ here) and the meat keeps coming until you can?t eat anymore. Expect incredibly delicious and succulent meat and a fantastic variety. Tempted? Check out our review here.

Brazil Churrasco is at 14 Sixth Avenue, 276476. Open daily 6pm ? 10.30pm. To make a reservation call 6463 1923.

J's (Purvis Street)

Just opened up on Purvis Street, 'J's' serves up a variety of alternative and traditional Latin cuisine such as Quesadillas, Adobo Chicken, Jalape?o poppers and the like. The dishes are surprisingly healthy- feeling, and most being served with fabulously fresh guacamole, salsa and sour cream. Excellent food, warm, welcoming staff, all at super reasonable prices. Full review coming soon...

J's is at 7 Purvis Street, 01-01, 188586. Open Monday - Friday 11.30am - 3pm and 6.30pm - 10pm, and Saturday 6.30pm - 11pm. Tel: 6887 4787.

Lucha Loco

Forget Americanized tacos with vast amounts of condiments ? it?s authentic Mexican street food which rules the roost at this Duxton joint that holds the spirit of a Mexican Taqueria. Think dishes packed out with fillings bursting with flavour and everything from octopus ceviche to toastaditas plus cracking drinks?their Mojitos are a must! Want to find out why else it had us going loco? See here.

Lucha Loco is at 15 Duxton Hill, 089598. Open Tuesday ? Thursday 4pm ? 11pm, Friday 4pm ? 1am and Saturday 6pm ? 1am.

SALTA Parilla

Going much beyond steak, which is a refreshing change when it comes to Argentinian restaurants, SALTA is also a great place to sample empanadas, Argentine salads, soups and much more - ?though of course the meat bursting with flavour is the main feature here. Want to find out more? Read our feature here.

SALTA Parilla is at Icon Village, 12 Gopeng Street #01-56, 078877. To make a reservation call: 6225 8443. Open Monday ? Saturday 11.30am ? 2.30pm and 6.30pm ? 10.30pm.

Senor Taco

With not one but four outlets now open here, this Mexican venture likes to show there?s life beyond just tacos and burritos with a varied and authentic menu. We were big fans of their Mexican brunch up at their Star Vista outlet but night owls be sure to check out their?Chjimes restaurant for a great dinner menu and an awesome tequila selection. Tempted by a Mexican brunch? Read our review here.

Senor Taco Chjimes is at 30 Victoria Street, 01-19/20. Open Sunday ? Thursday 6pm ? midnight and Friday ? Saturday 6pm ? 2am. Senor Taco Star Vista is at 1 Vista Exchange Green, 02-22, The Star Vista, 138617. Open Sunday ? Tuesday & Thursday 12pm ? 11pm, Wednesday 12pm ? 2am, and Friday 12pm ? midnight.

Viva Mexico

An older kid on the block, though we have to admit we are not huge fans of Cuppage Terrace, it has to be said that it?s worth heading there for a visit to Viva Mexico. Another place which comes up on our radar for tasty, pretty authentic Mexican fare ? with a true blue Mexican chef at the helm, this one had us pleasantly surprised and is a decent option if you?re craving some Mexican colour.

Viva Mexico is at 23 Cuppage Road, Cuppage Terrace. Open daily 12pm ? 2.30pm and 6pm ? 11.30pm. To make a reservation call 6681 6670.

Sur Nuevo Latin Kitchen

The newest kid on the block, Sur features flavours from around South America whipped up by two South American chefs no less, served up in an imtimate setting. Expect an interesting menu which includes everything from?crispy pork belly, a variety of ceviche, and some rather delicious desserts!

Sur Nuevo Latin Kitchen is at 13 North Canal Road, 01-01, 048826. Open Monday ? Friday 11.30am ? 3pm and 5.30pm ? 10.30pm and Saturday 5.30pm ? 10.30pm. To make a reservation call 6222 2897.

Well Nomads, this list is by no means exhaustive ? just our favourite picks. There are also other players on the scene worth checking out, including Baja Fresh Mexican Grill,?Piedra Negra and Caf? Iguana. But for now, we say, hasta luego!


Written by Ms Demeanour. ?Like my chat? Friend me on Facebook?here!

Posted in: Latin American Meat-lovers Mexican Restaurants

Various locations around Singapore

Source: http://www.citynomads.com/reviews/latin-american/350/ay-caramba-singapores-best-latin-american-restaurants

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Microsoft Office 365 Home Premium review

Microsoft Office 365 Home Premium review

It feels like we've been talking about Office 2013 for a while now -- we first previewed the software back in July, and it's been available as a free beta download ever since. Today, though, it's launching in a more formal way: the final version of Office 2013 is now on sale, as is Office 365 Home Premium, which lets you purchase a subscription to Office 2013 and then install it on up to five computers.

Though you can still buy the software outright, Microsoft has gone out of its way to make subscribing seem like the more attractive option: buying a one-year subscription costs $100 a year and nets you five installs, while the purchase cost is $139 for a single user. To sweeten the deal, Microsoft is giving Office 365 subscribers 60 Skype minutes per month, and expanding the standard SkyDrive limit from 7GB to 20GB. Naturally, too, subscribing to the service means you always get the latest software -- a particularly important point for Apple fans still waiting on a new version of Office for Mac. Either way, though, Office 2013 now has an app store, and you can poke around even if you're not a subscriber.

As it is, we've already given you an in-depth walk-through of all the major new features in Office, but we haven't yet gotten to experience it as a subscription, with all our settings following us from one PC to another. But we're still wondering: is it worth shelling out a hundred bones a year for a subscription?

Getting started


Though Office 2013 and Office 365 will both be available to purchase in stores, you won't actually find an installation CD in the box. Even if you buy it from a brick-and-mortar kind of place, you'll only really see a written product key when you tear open the packaging. So, regardless of whether you purchase in stores or online, you'll eventually need to head over to office.com, enter your license number and then proceed to download the software.

As ever, the system requirements are fairly modest: so long as you have 3.5GB of free disk space and an x86 or x64 system clocked at 1GHz or higher, you'll be good to go. DirectX10 graphics are required, along with a minimum resolution of 1,024 x 576. Microsoft also recommends 1GB of RAM for 32-bit systems and 2GB for 64-bit machines.

In any case, once you enter your product key it's smooth sailing. Just sign in with your Microsoft account (you'll have a chance to create one if you're a new user) and verify your country and language. So far so good, right? From that home screen on office.com, you can see how many of your five installations you've used. You can view your payment method, expiration date, billing history and automatic renewal information, if applicable. And, of course, there's a big "install" button, which you'll need to click since you haven't actually downloaded the software yet.

DNP Microsoft Office 365 Home Premium review

While Office sets itself up for the first time, you can choose to page through a few introductory slides. All told, it's not unlike how Windows 8 loads a primer on new gestures while the OS readies itself for the first time. Naturally, once they're fully installed the various Office apps appear as Live Tiles on the Start Screen, not as desktop shortcuts.

Once you've installed Office, you can sign in to your Microsoft account (or not -- in which case it's just a local copy). You can also choose the border that will appear on new Word documents and other files. In all, there are 14 of these themes, though there's also a "no background option" for people who find doodles of circles and circuits offensive. Not that we're pressuring you or anything, but they're really very subtle: they only take up a small patch of space on the fringe of the screen, and don't actually call much attention to themselves.

Office 2013


DNP Microsoft Office 365 Home Premium review

As crazy as this might sound, we don't plan on dwelling too much on the actual Office suite, just because we already wrote thousands of words on the subject back when it was first released. For a full run-down of the new features (plus dozens of screenshots), we'll direct you back to our preview, first published six months ago. For those of you who lack the attention span, though, we'll humor you with a quick recap. Notable new features in the suite include PDF editing in Word, a full-screen Reading Mode (great for tablets) and a behind-the-scenes Presenter View in PowerPoint. Touch Mode is exactly what it sounds like, which is to say it makes all the UI elements a little bigger and more touch-friendly -- not that it magically makes Excel convenient to use without a keyboard, per se. Resume Reading remembers exactly where you were in a document the last time you opened it, which is useful if you've been charged with editing a 40-page patent infringement brief or something equally tedious.

Even when the software was still in development we found it to be fast and stable, while the features themselves were intuitive to use.

By default, the various Office apps now save to SkyDrive, and you can always send someone a link to your work so they can read it in a browser. Adding online video to Word and PowerPoint files is much easier than it had been, and it's now possible to reply to comments in Track Changes. Flash Fill in Excel can predict what information should go in blank cells if the data is repetitive and follows a pattern. Finally, Outlook gets a feature called Peeks, which lets you hover to view your calendar and such without leaving the inbox. Meanwhile, so-called Social Connectors are plug-ins from services like LinkedIn.

For the most part, the software is the same as when we last tested it. And that's a good thing: even when the software was still in development we found it to be fast and stable, while the features themselves were intuitive to use. The only point of controversy might be the carryover of the Ribbon UI, which debuted all the way back in Office 2007, and which some people still haven't warmed up to.

There are a few new features, however, many of them subtle fit-and-finish sort of things. The icon for switching to Touch Mode has changed, and when you tap it you now get a pop-up menu that briefly explains the difference between that and mouse mode (the gist being that in Touch Mode there's no Ribbon menu, and the various UI elements are spaced farther apart). There's also a rotating group of templates, which vary depending on region and also the time of year. For instance, you won't see any Valentine's Day-related options in August, and you also won't see any sample Fourth of July party invites if you live outside the US. It's a smart idea, making these things timely and region-specific. We're not sure how many people actually use templates to begin with, but if you do, knock yourself out.

PowerPoint, meanwhile, has gotten a new transitions category called "Exciting," which includes some new animations. As you might have guessed, they're flashy transitions, sequences with names like "Curtains," "Origami" and "Paper Airplane" (they all are exactly what they sound like). What can we say? They're playful and call lots of attention to themselves, which is to say they probably won't be especially welcome at a board meeting. But just like with the templates, we're glad they're there for people who require a few more resources to truly express themselves.

Office Store


DNP Microsoft Office 365 Home Premium review

Now that Microsoft has dragged Office kicking and screaming into the cloud-computing era, it's doing something else to bring the software up to date: it's giving the suite its very own app store. The Office Store lives on office.com, and is accessible even to folks who don't have a subscription to Office 365 (meaning, it's fine if you just own Office 2013). So far, the store includes apps for Word, Excel, Outlook, Project and SharePoint (but not PowerPoint, strangely). If you like, you can sort apps by any of the above programs, which is how we prefer to go about it. Alternatively, though, you can browse through a page of features apps, too. Similar to the Windows Store, you can read user reviews and click through to see detailed system requirements. Installing an app is as easy as hitting an "Add" button, though you'll need to go through an extra step to make sure it appears in the Ribbon of whatever Office application uses the add-on.

What's interesting about browsing the store is that because no one really expected or asked for Office applications, it doesn't matter so much how many there are, or whether you've heard of any of them. (In other words, this isn't like demanding Instagram on Windows Phone 8 and accepting no substitutes.) In fact, there are some big names represented, including LinkedIn, which has a plug-in for Outlook, and Merriam-Webster, whose dictionary works across Word and Excel. We also found some other apps we could see ourselves using, like Bing News for Word and "Random Generator" for Excel.

Most of these are free, which creates a nice incentive for downloading a bunch and seeing what sticks. (As you can see, "nice and inoffensive" seems to be a running theme here, at least as far as the new features go.) A few of the apps do cost money, however, particularly some of the more sophisticated programs designed for enterprise users. If you're a developer reading this, Microsoft takes a 20 percent cut from application purchases, which matches the revenue split already in place for Windows applications.

DNP Microsoft Office 365 Home Premium review

To use the apps, just click the Insert in the Ribbon, followed by "Office Apps." Each one shows up as a pane along the right-hand side, which you can easily close by tapping an "X" button. You can open more than one app at once (as evidenced in the screenshot above) but be warned: for every app you open, you'll have less space to actually do your work. The apps in Word, for instance, line up side by side, causing the actual document to narrow. If you only open up one application, you'll still be able to type in Word without having to do any extra scrolling from side to side; that changes once you open a second app, though. All told, it's a minor inconvenience: just decide whether you need to be using Bing News at the moment, or if Merriam-Webster is more vital.

As for the apps themselves, they're exactly what they sound like, and that's a good thing. Bing News has a search bar into which you can type queries. Ditto for the dictionary app we tried, and LinguLab WordCloud. Web searches, definitions and everything else shows up in the same box where you performed the search so that you don't have to toggle over to IE 10 -- or any other program, for that matter. That alone makes these apps useful, though it helps that the information itself is clearly presented and comes from reliable sources.

Wrap-up


DNP Microsoft Office 365 Home Premium review

What can we say? Office 2013 is a top-notch product: fast, intuitive and feature-rich. All of the new features work as promised, and are easy to get the hang of. At the same time, since the UI is similar to the previous version, it should be easy to master if you're upgrading from Office 2010. Now it's true, there are various free alternatives out there, including cloud-based ones like Google Docs. Still, we're wary of steering all our readers there, because we know lots of folks are already comfortable using Office, or have come to rely on some of the more advanced features you can't get elsewhere. Assuming you don't have any interest in switching to a more basic suite, then, the real question is: does it make more sense to buy Office once for $139 and make do with one license? Or is it wiser in the long run to pay $100 every year for a subscription in exchange for five installations and ongoing software updates?

Obviously, the more computers you own, the more it makes sense to pay $100 a year for five activations. For example, buying five individual copies would cost $695 up front, as opposed to $600 for six years of service. Basically, you'd be saving money until that seventh year rolls around, and that's a long enough stretch that you'd get upgraded to Office 2017 in the interim. That said, the subscription model isn't for everyone. Many of the perks -- Skype minutes, extra SkyDrive storage -- seem like weak reasons to go with Office 365 if you're on the fence. Meanwhile, the Office Store is useful but it's not like you need a subscription to enjoy it. With all that in mind, if you own just one machine it might make sense to shell out $139 for a single license and not have to pay $100 on an annual basis. In short, then, Office itself is a polished product, but your decision on whether to get 2013 or 365 should mainly come down to how many computers you own. Almost everything else is beside the point.

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Source: http://feeds.engadget.com/~r/weblogsinc/engadget/~3/DmMAipylXvY/

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Tuesday, January 29, 2013

Apple prepping 128 GB iPad model: report

5 hrs.

Leaked inventory listings suggest that Apple will soon launch a 128 GB version of its popular iPad. That would give it twice the storage of the largest iPad available now, reportedly for a $100 premium.

The information comes from a few sources, with code in the latest Apple?iOS and iTunes releases suggesting upcoming 128GB devices, and more recently from an inventory listing leaked to 9to5Mac.com.

The listing has iPads at prices $100 over the existing models, totaling $799 for a Wi-Fi only version, or $929 for a cellular-enabled one. The description in the listing is "ultimate," which makes sense: Existing 16, 32?and 64 gigabyte iPads have been described in inventory descriptions as "good," "better" and "best" respectively.

Together, the pricing and description are highly suggestive of a new 128?GB iPad model, but there's nothing yet to indicate timing. Apple's release schedule has grown?increasingly difficult to predict, and while the last iPads were unveiled in October, the company previously updated the device line earlier in the year.

Some think that an early-2013 event will bring the larger iPad model and some other refreshes to existing product lines, while brand-new versions of both the iPhone and iPad will be released later in the year, possibly in October. NBC News contacted Apple for comment; if we hear back, we'll update this post.

Devin Coldewey is a contributing writer for NBCNews Digital. His personal website is?coldewey.cc.

Source: http://www.nbcnews.com/technology/gadgetbox/apple-prepping-128-gb-ipad-model-report-1C8150691

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NewVoiceMedia Takes $20M Led By Highland Capital, MMC To Build Contact Centers In The Clouds

linuxcon-cloudsNewVoiceMedia, an enterprise startup riding the wave of cloud-based services, has raised $20 million for its business of contact center solutions, which currently serves 8,000 agents in 30 countries. The Series B round was led by Highland Capital Partners and MMC, with participation from existing investors Eden Ventures and Notion Capital, and brings the total funding for NVM to $26.3 million.

Source: http://feedproxy.google.com/~r/Techcrunch/~3/xg2Vss9Gl5s/

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Researchers identify new target for rheumatoid arthritis

Monday, January 28, 2013

Researchers at Hospital for Special Surgery have identified a potential new target for drugs to treat patients with rheumatoid arthritis (RA), a protein known as IRHOM2. The finding could provide an effective and potentially less toxic alternative therapy to tumor necrosis factor-alpha blockers (TNF-blockers), the mainstay of treatment for rheumatoid arthritis, and could help patients who do not respond to this treatment. Efforts to develop drugs that hone in on this new target are underway.

"This study is an elegant example of the capacity of basic science cell biologists to work with translational rheumatologists to address a clinically relevant question at a basic level," said Jane Salmon, M.D., Collette Kean Research Chair and co-director, Mary Kirkland Center for Lupus Research at Hospital for Special Surgery (HSS) in New York City, and an author of the study. "We have identified a clinically relevant target that can be applied to patients in the near term." The study will appear online, ahead of print, on January 25, in the Journal of Clinical Investigation and in the February 2013 print issue.

Rheumatoid arthritis, an autoimmune disease, is triggered, in large part, by TNF-alpha, a small signaling protein usually involved in launching protective systemic inflammatory responses. With excessive TNF production, however, immune cells can become activated inappropriately and cause tissue inflammation. This produces a number of diseases, including RA. While TNF-blockers help many RA patients, these treatments are very expensive, and some patients do not respond. For this reason, researchers have been searching for alternative targets in patients with inflammatory diseases against which drugs can be directed.

"TNF can be thought of as a balloon tethered to the surface of cells. To work, it must be cut loose by signaling scissors called TACE (TNF-alpha converting enzyme)," said Carl Blobel, M.D., Ph.D., program director of the Arthritis and Tissue Degeneration Program at HSS. While blocking TACE could be another way to treat rheumatoid arthritis, researchers know this strategy would likely have side effects since patients lacking TACE are prone to skin infections and intestinal lesions.

Earlier this year, HSS investigators demonstrated that the TACE scissors are regulated by molecules called IRHOM1 and IRHOM2, which are thought to wrap around TACE and help it mature into functional scissors. They also demonstrated that mice that are genetically engineered to lack IRHOM2 lack functional TACE on the surface of their immune cells and don't release TNF. Surprisingly, these mice are healthy, and do not develop skin or intestinal defects.

In the current study, HSS researchers set out to investigate why this paradox exists. After examining tissues of IRHOM2-deficient mice, they found that IRHOM2 regulates TACE on immune cells, whereas IRHOM1 is responsible for helping TACE mature elsewhere in the body, such as in brain, heart, kidney, liver, lung and spleen cells. "IRHOM2 appears to have a more restrictive and exclusive function in immune cells," said Dr. Blobel.

The researchers then set out to determine whether blocking IRHOM2 could be a strategy to treat RA. They used a mouse model that mimics human rheumatoid arthritis in mice genetically engineered to be deficient in IRHOM2. They found that these rodents did not develop inflammatory arthritis and were otherwise healthy.

"When we tested mice that don't have IRHOM2 in a model for inflammatory arthritis, we found they were protected and they were protected as well as mice that didn't have any TNF," said Dr. Blobel. "Because TNF is the driver of rheumatoid arthritis in human disease, as evidenced by how well anti-TNF drugs work, we feel that this provides a completely new angle on blocking TNF release. It would be wonderful to be able to inactivate TACE in a tissue-specific manner and IRHOM2 provides a unique mechanism for us to do so."

Using drugs that inactivate IRHOM2 in humans, clinicians will be able to block the function of TACE only in immune cells. "We can prevent the deleterious contribution of TACE to rheumatoid arthritis patients and preserve its protective function in skin and intestines," said Dr. Blobel. "With IRHOM2, we have a unique and unprecedented opportunity to inactive TACE only in certain cell types, and not in others, and there is currently no other effective way of doing that."

The researchers say the next step is to identify antibodies or pharmacological compounds that can be used to block the function of IRHOM2 and are safe in patients. These HSS investigators are currently working to identify and test such agents. "In theory, IRHOM2-targeted drugs will have less toxicity than TNF alpha blockers," said Dr. Salmon. "They block TNF release only from specific cells, those known to contribute to joint inflammation and damage."

###

Hospital for Special Surgery: http://www.hss.edu

Thanks to Hospital for Special Surgery for this article.

This press release was posted to serve as a topic for discussion. Please comment below. We try our best to only post press releases that are associated with peer reviewed scientific literature. Critical discussions of the research are appreciated. If you need help finding a link to the original article, please contact us on twitter or via e-mail.

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Source: http://www.labspaces.net/126480/Researchers_identify_new_target_for_rheumatoid_arthritis

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Monday, January 28, 2013

Ocala Veterinarian Partners With PETS for Emergency Veterinary Care

OCALA, Fla., Jan. 27, 2013 (GLOBE NEWSWIRE) -- An Ocala pet wellness veterinarian wishes to spread the word about his hospital's partnership with an after-hours emergency facility. Town & Country Animal Hospital refers emergency cases that occur outside of its normal operating hours to PETS (Pet Emergency Treatment Services). "We are proud to be associated with this advanced after-hours emergency care center," says Kelly Culbertson, DVM. "We want our patients to receive a high standard of emergency veterinary care as quickly as they can possibly get it. Our referral relationship with PETS helps to ensure that this will happen."

PETS is an organization of local veterinarians in cooperation with the University of Florida College of Veterinary Medicine. The centrally-located clinic offers emergency care from 5pm to 8am on weekdays, and around the clock on weekends, to meet the needs of pets that require immediate attention when most veterinary centers are closed.

"Unfortunately, an emergency doesn't always happen during business hours," observes Dr. Culbertson. "A crisis situation such as choking, toxin ingestion or a traumatic accident can occur any time of day or night. PETS is our answer to this need for after-hours emergency care."

Other typical pet emergency scenarios include vomiting, diarrhea, respiratory or heart problems, neurological crises, bloat, abdominal pain, and complications from a chronic illness. Town & Country Animal Hospital will automatically forward after-hours emergency calls to the PETS clinic. A full staff of assistants and technicians stand by to help the emergency vets deal with incoming cases.

While Town & Country Animal Hospital provides comprehensive emergency and critical care services, including blood transfusions, it closes at 6pm on weekdays and at 12pm on Saturdays (remaining closed on Sundays). Town & Country Animal Hospital is one of 19 area veterinary hospitals involved with the organizations since its founding in 2012. Dr. Culbertson himself helped bring the organization to fruition, and he continues to sit on its board.

His central message, however, is that pet owners realize that they have a place to turn for round-the-clock emergency care. "If your pet suffers an emergency at 2 in the morning or on a Sunday, don't panic," Dr. Culbertson says. "Contact PETS to get the immediate treatment your pet might need."

Town & Country Animal Hospital provides emergency and critical care, dental care, boarding, grooming, surgery, general wellness care and other services for pets in Ocala, Silver Springs, Marion County, Williston and Morriston.

Town & Country Animal Hospital 888-667-5235

Source: http://globenewswire.com/news-release/2013/01/27/518723/10019328/en/Ocala-Veterinarian-Partners-With-PETS-for-Emergency-Veterinary-Care.html

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Egyptian youths, police clash in fourth day of street violence

CAIRO (Reuters) - Police fired tear gas at dozens of stone-throwing protesters in Cairo on Sunday in a fourth day of street violence that has killed at least 41 people and compounded the political challenges facing President Mohamed Mursi.

The most deadly clashes flared up in Port Said where 32 people were killed on Saturday alone. That violence was provoked by a court verdict sentencing 21 people, mostly from the city, to death for their role in a deadly stadium disaster last year.

But protests have been going in cities across Egypt since Thursday led by opponents of Mursi and his Islamist allies. Demonstrations were initially timed to mark Friday's second anniversary of the uprising that overthrew Hosni Mubarak.

Opponents say Mursi has betrayed the goals of the revolt.

The army, Egypt's interim rulers until Mursi's election June, were sent back onto the streets to restore order in Port Said and Suez, another port city on the Suez Canal where at least eight people have been killed in clashes with police.

Although scuffles continued on Sunday morning in Cairo, there was no immediate sign of the kind of deadly escalation of previous days in the capital or elsewhere.

The spasm of violence adds to the daunting task facing Mursi as he tries to fix a beleaguered economy and cool tempers before a parliamentary election expected in the next few months which is supposed to cement Egypt's transition to democracy.

It has also exposed a deep rift in the nation. Liberals and other opponents accuse Mursi of failing to deliver on economic promises and say he has not lived up to pledges to represent all Egyptians. His backers say the opposition is seeking to topple Egypt's first freely elected leader by undemocratic means.

"Till now, none of the revolution's goals have been realized," said Mohamed Sami, a protester in Tahrir Square. "Prices are going up. The blood of Egyptians is being spilt in the streets because of neglect and corruption and because the Muslim Brotherhood is ruling Egypt for their own interests."

On a bridge close to Tahrir Square, youths were hurling stones at police in riot gear who fired tear gas to push them back towards the square which was the cauldron of the uprising that erupted on January 25, 2011 and toppled Mubarak 18 days later.

The U.S. embassy in Cairo, which is near Tahrir Square, said it was suspending public services on Sunday "due to the security situation in the vicinity" of the mission.

Many Egyptians are frustrated by the regular escalations that have hurt the economy and their livelihoods.

"They are not revolutionaries protesting," said taxi driver Kamal Hassan, 30. "They are thugs destroying the country."

CALL FOR DIALOGUE

The National Defense Council, headed by Mursi and including top army and other officials, has called for a national dialogue to discuss political differences.

That offer has been cautiously welcomed by the opposition National Salvation Front. But the organization has demanded a clear agenda and guarantees that any agreements will be implemented.

The Front, formed late last year when Mursi provoked protests and violence by expanding his powers and driving through an Islamist-tinged constitution, has threatened to boycott the parliamentary poll and to call for more protests if a list of demands is not met, including having an early presidential vote.

Egypt's transition has been blighted from the outset by political rows and street violence that have driven investors out and kept many tourists away, starving the economy of vital sources of hard currency.

Clashes in Port Said erupted after a judge sentenced 21 men to die for involvement in the deaths at a soccer match on February 1, 2012 between Cairo's Al Ahly club and the local al-Masri team. Many of the victims were fans of the visiting team.

There were 73 defendants in the case. Those not sentenced on Saturday will face a verdict on March 9, the judge said.

Al Ahly fans cheered the verdict after threatening action if the death penalty was not meted out. But Port Said residents were furious that people from their city were held responsible, triggering wild rampages through the streets.

A security source in Port Said said 32 people were killed, many from gunshot wounds. More than 300 were injured in one of the most deadly eruptions of violence during the past two years.

Clashes have also flared in Cairo, Alexandria and Port Said. Eight people died in Suez on Friday and police clashed with protesters again on Saturday.

Officers fired teargas when protesters angry at Friday's deaths hurled petrol bombs and stormed a police post and other government buildings. Around 18 prisoners escaped from police stations and stole some weapons, a security source said.

Reflecting international concern, British Foreign Office Minister for the Middle East Alistair Burt said: "This cannot help the process of dialogue which we encourage as vital for Egypt today, and we must condemn the violence in the strongest terms."

European Union foreign policy chief Catherine Ashton urged the Egyptian authorities to restore calm and order and called on all sides to show restraint, her spokesperson said.

(Editing by Andrew Heavens)

Source: http://news.yahoo.com/riots-over-egyptian-death-sentences-kill-least-32-005245042.html

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Sunday, January 27, 2013

jobsanger: Human Family Tree

Quote

It is through disobedience and rebellion that progress has been made.
-Oscar Wilde

Quote

If you're in trouble, or hurt or need - go to the poor people. They're the only ones that'll help - the only ones.
-John Steinbeck

Quote

What you need is sustained outrage...there's far too much unthinking respect given to authority.
-Molly Ivins

Comment Policy

I invite anyone who wishes to comment on this blog to do so. I enjoy the comments, whether you agree with what I have said or not. But some people want to abuse the right to comment, and since this is my blog, I have decided to lay down the following rules. If your comment violates these rules, it will not be published.

1. Comments must not be racist, misogynistic, homophobic, or otherwise bigoted.

2. Comments must not involve little more than name-calling and insulting remarks.

3. Comments must not be made by "anonymous".

4. Comments must not try to sneak in some free advertising for themselves (like spam).

Source: http://jobsanger.blogspot.com/2013/01/human-family-tree.html

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Star Wars VII: The force is strong in J.J. Abrams

Disney confirmed that J.J. Abrams, of 'Lost' and the new 'Star Trek' movies, will direct the newest 'Star Wars' movie, set to be released in 2015. Abrams will consult with one of the writers from the original trilogy.

By Associated Press / January 26, 2013

J.J. Abrams arrives at the Winter TCA Fox All-Star Party at the Langham Huntington Hotel in Pasadena, Calif., Jan. 8. Abrams is set to direct the next installment of 'Star Wars,' which Disney has said will be 'Episode 7' and due out in 2015.

Matt Sayles/Invision/AP/File

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It's official. The force is with J.J. Abrams.

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The Walt Disney Co. issued a statement Friday night confirming reports that had been circulating for two days that Abrams, Emmy-award-winning creator of TV's "Lost" and director of 2009's "Star Trek" movie, has been pegged to direct the seventh installment of the "Star Wars" franchise.

"J.J. is the perfect director to helm this," said Kathleen Kennedy, the movie's producer and president of Lucasfilm, which was acquired by Disney last month for $4.06 billion.

"Beyond having such great instincts as a filmmaker, he has an intuitive understanding of this franchise. He understands the essence of the Star Wars experience," Kennedy said in the statement.

The movie will have a script from "Toy Story 3" writer Michael Arndt and a 2015 release.

Lawrence Kasdan, who wrote "The Empire Strikes Back" and "Return of the Jedi" in the original trilogy, will work as a consultant on the new project.

Abrams has already headed the reboot of another storied space franchise, "Star Trek," for rival studio Paramount Pictures. The next installment in that series, "Star Trek: Into Darkness," is set to hit theaters May 17.

But he has long been known as a "Star Wars" devotee. Abrams spoke about the plot of the original "Star Wars" in the lecture series "TED Talks" in March 2007, and reportedly became enamored of "Lost" co-creator Damon Lindelof partly because Lindelof was wearing a "Star Wars" T-shirt when they first met.

In 2009, Abrams told the Los Angeles Times: "As a kid, 'Star Wars' was much more my thing than 'Star Trek' was."

In Friday night's statement he called it an "absolute honor" to get the job.

"I may be even more grateful to George Lucas now than I was as a kid," Abrams said.

Lucas himself said in the statement that "I've consistently been impressed with J.J. as a filmmaker and storyteller. He's an ideal choice to direct the new Star Wars film and the legacy couldn't be in better hands."

Source: http://rss.csmonitor.com/~r/feeds/csm/~3/CN1MzvGONDk/Star-Wars-VII-The-force-is-strong-in-J.J.-Abrams

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Illinois to allow immigrants to get licenses

SPRINGFIELD, Ill. (AP) ? Illinois is the fourth state to allow illegal immigrants to obtain a driver's license with a new law signed by the governor.

Democratic Gov. Pat Quinn signed the legislation Sunday surrounded by hundreds of supporters who say the measure will make Illinois' roads safer and expand opportunities for illegal immigrants.

Quinn says people need a way to get to work, drive to the doctor and drive their children to school. Chicago Mayor Rahm Emanuel says the new law should serve as a model for the nation.

New Mexico and Washington both issue licenses to undocumented immigrants, while Utah issues permits.

Illinois officials say the dissemination of the temporary licenses is expected to begin in November.

The legislation was billed as a public safety measure and had bipartisan support.

Source: http://news.yahoo.com/illinois-allow-immigrants-licenses-221430757.html

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P53 mutation hinders cancer treatment response

Jan. 25, 2013 ? Scientists from the National Cancer Centre Singapore (NCCS) have discovered the workings of the gene that has been hindering treatment response in cancer patients. This discovery was made after 5 years of studying the mutant form of the p53 gene, the major tumor suppressor in humans, which is generally found mutated in over 50% of all type of human cancers.

The dominant-negative (DN) effect of the mutant p53 gene in cancers was found to affect the outcome of cancer treatment modalities. DN effect is a phenomenon whereby one copy of mutant p53 that exists in cancer cells inhibits the tumor suppressor activity of the other wild-type p53 copy when they co-exist. The result is that a patient may either have poor response or earlier relapse of tumours after their treatment.

The research findings is significant in that it offers hope to improve cancer treatment outcomes by selectively inhibiting mutant p53's DN effect through several methods by generating selective and specific inhibitory molecules specific for some of the common hot-spot p53 point mutations. There are currently no drugs or compounds that can alleviate DN effects of mutant p53.

In order to understand the specific roles of mutant p53 DN properties in regulating acute treatment response and long-term tumourgenesis, a team of five researchers led by NCCS Prof Kanaga Sabapathy, the Principal Investigator in the Laboratory of Carcinogenesis and Head of the Division of Cellular & Molecular Research from NCCS, carried out experiments by generating genetically engineered knock-in mouse strains expressing varying levels of mutant p53. The results showed that DN effect is observed after acute p53 activation by a variety of chemotherapeutic drugs and irradiation, thereby affecting anti-cancer treatment. This breakthrough came after five years of intensive research.

It was found that mutant p53 have DN effects in a cell-type and dose-dependent manner, especially during acute p53 activation where p53 levels are elevated. Based on the above observations, efforts to generate specific inhibitors for the common hot spot p53 point mutations are underway. The inhibition of mutant p53 expression in cells carrying a wild-type and mutant p53 alleles can improve response to chemotherapeutic drugs.

In a further study, the researchers also questioned the possibility of the mutant p53 acquiring new functions (or Gain of Function) to drive carcinogenesis, transforming normal cells to cancerous cells. Their investigation comparing cells from genetically engineered mouse strains expressing 2 different types of p53 mutations: the R172H mutation versus the R246S mutation, which showed that Gain of Function (GOF) was found only in the former. This showed that GOF of mutated p53 is specifically dependent on mutation-type but not across all kinds of genetic mutations, highlighting diversity in properties of the different types of p53 mutations, thereby indicating that mutations found in human cancers can behave differently, and thus, need to be carefully assessed prior to treatment.

Thus, the existence of mutant p53 certainly has a negative impact on cancer treatment, whether it is through DN effect or GOF. Prof Sabapathy said that the team is now embarking on more research to determine the possibility of targeting mutant p53 without affecting wild-type p53 in human cells, paving way to clinical trials in the future to test the efficacy on cancer therapeutic response.

The research was supported by grants from the National Medical Research Council of Singapore and the Singapore Millennium Foundation to KS. The publication has been accepted and published by Cell Press, publisher of biomedical journals, in the journal Cancer Cell, on Dec. 10, 2012. Prof Sabapathy also teaches at the Duke-NUS Graduate Medical School.

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The above story is reprinted from materials provided by SingHealth, via EurekAlert!, a service of AAAS.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:

  1. Ming?Kei Lee, Wei?Wei Teoh, Beng?Hooi Phang, Wei?Min Tong, Zhao?Qi Wang, Kanaga Sabapathy. Cell-type, Dose, and Mutation-type Specificity Dictate Mutant p53 Functions In?Vivo. Cancer Cell, 2012; 22 (6): 751 DOI: 10.1016/j.ccr.2012.10.022

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/~3/EAuE68IgufU/130125111331.htm

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What Are The Basics Of Sport Fishing?

One of the most import things to know about sport fishing in Costa Rica is that the fishing is actually angling, that is, catching fish with a pole, line, and hook. It is not spear fishing, netting, or trapping. There are two parts to the fishing: attracting your target fish to the hook and landing the fish, otherwise known as reeling in your catch. Both parts are enhanced by superior knowledge and experience of the angler. The challenge is what makes the art of fishing so much fun.

The first challenge for Costa Rica sport fishing comes when attempting to attract the fish to the hook. Many anglers use live bait as a way to entice the fish. The type of bait used depends heavily on the target fish, but can also differ according to the time of day, the movement of the water, and the season. Many anglers are anxious to begin, and simply ask their charter leaders to recommend a type of bait. Although this will give a quick and accurate answer, many anglers prefer to take their time and carefully research their choices. They will spend hours in the fishing lodge and elsewhere, discussing the various bait and the success rate of each. To this type of angler, just asking the charter leader would mean missing out on one of the best parts of the fishing experience.

Other anglers prefer to make artificial bait, known as lures, for their fishing in Costa Rica. Although the lures will not naturally release attractive chemicals into the water, their movement better simulates life. Most fish prefer live food, and will in fact often prefer lively to alive. In other words, they would prefer a lure that moves like an active minnow to an actual minnow that is not alive, but just lying torpid in the water. The range and imagination put into making lures knows no bounds. An outsider would be safer discussing religion and politics with an angler, than to declare one type of lure to be better than another.

The second part of the challenge for sport fishing in Costa Rica is landing the fish, once the fish has taken the bait. The fish will quickly recognize the pulling pressure of the line, and its flight instinct will kick in right away. The trick is to avoid a tug-of-war. This is because the fish of Costa Rica are big enough to break the line in a direct contest of strength. The secret to landing the fish is to play with it, reeling for a time and then letting the fish run with the line, until it becomes fatigued. This means that you gently reel it in, then let it make a run, and repeat the process until the fish is tired enough to be brought in. These are the basics of sport fishing.

About the Author:
Chaser Sport Fishing invites you to join us for a unique fishing adventure in beautiful Quepos, Costa Rica. From sailfish to marlin, dorado or tuna to wahoo and rooster fish, the skilled team of captains and crew at Chaser Sport Fishing has the expertise to help you relax, have a great time and catch fish in Costa Rica. Visit chasersportfishing.com to learn about booking a trip with Chaser Sport Fishing.

Source: http://www.articlesnatch.com/Article/What-Are-The-Basics-Of-Sport-Fishing-/4400942

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Saturday, January 26, 2013

Syrian troops fight rebels in Damascus suburb

In this image taken from video obtained from the Sham News Network, which has been authenticated based on its contents and other AP reporting, a pair of what activists say are tanks from President Bashar Assad regime in sit in a street in the Daraya neighborhood of Damascus, Syria, just before one of them fires a shot Friday, Jan. 25, 2013. Troops battled rebels around Damascus in an effort to dislodge opposition fighters who have set up enclaves around the capital, including Daraya and Zabadani. (AP Photo/Sham News Network via AP video)

In this image taken from video obtained from the Sham News Network, which has been authenticated based on its contents and other AP reporting, a pair of what activists say are tanks from President Bashar Assad regime in sit in a street in the Daraya neighborhood of Damascus, Syria, just before one of them fires a shot Friday, Jan. 25, 2013. Troops battled rebels around Damascus in an effort to dislodge opposition fighters who have set up enclaves around the capital, including Daraya and Zabadani. (AP Photo/Sham News Network via AP video)

In this image taken from video obtained from Bambuser, which has been authenticated based on its contents and other AP reporting, men help an injured and heavily bleeding man through the rubble of a building that was destroyed following what activists said were two airstrikes in the Arbeen neighborhood of Damascus, Syria, Friday, Jan. 25, 2013. (AP Photo/Bambuser via AP video)

BEIRUT (AP) ? Syria's state-run news agency says troops have raided an opposition stronghold near Damascus, killing an unspecified number of rebels and uncovering tunnels used by them to move about and smuggle weapons.

SANA says the tunnels were discovered Saturday after clashes in Daraya just south of the capital.

Two activist groups, the Britain-based Syrian Observatory for Human Rights and the Local Coordination Committees, meanwhile reported shelling and air raids of other Damascus suburbs, including areas near the international airport.

Syrian troops have been trying to capture Daraya for weeks but faced strong resistance from hundreds of rebels. Damascus suburbs have been used as a base by rebels to threaten nearby regime facilities.

Syria's crisis began in March 2011 and has so far killed more than 60,000 according to the U.N.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/cae69a7523db45408eeb2b3a98c0c9c5/Article_2013-01-26-ML-Syria/id-47d9b04ec77d4713874e24d1404491b3

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Friday, January 25, 2013

Wile E. Coyote Teaches Math (And Despair) To Lucky Students In New Zealand

There's something about being upside down (from all of us in the Northern Hemisphere) that makes New Zealanders a little melancholy. At least that's my theory.

My evidence? Well, the other day, I was looking at a curriculum guide for math teachers ("maths" teachers, they would say) on the New Zealand Ministry of Education's site, where the text on top says, We want to equip "all New Zealanders with the knowledge, skills, and values to be successful citizens in the 21st century."

When you flip to the Maths page, here's what they think young citizens should know: Let's test, they say, the truth or falsity of Murphy's Law.

Not a cheery choice. You know Murphy's Law, right? It says, "Anything that can go wrong, will go wrong." The folks at the Ministry don't like snappy English, so they wrote it this way:

"In this unit, students will explore the commonly held believe (sic) that if anything bad can possibly happen it will and at the most inopportune time."

It's fun to read the list of supplies teachers should bring to the classroom, the step-by-step instructions, (you can do that here) but what I liked best were the examples, the case studies. They are so painfully specific.

The Ministry says it's teaching statistics, but really it's teaching the philosophy of Wile E. Coyote of the Road Runner cartoons. These lessons look like math, not so deep down they are an immersion into the World of Despair. The Ministry recommends five examples of Murphy's Law. I've translated from New Zealand English when necessary. These are exact quotations.

"The first lesson will investigate the example of Murphy's Law relating to keys. It goes like this (act it out as you are saying it): There you are carrying a heavy box of things to the door or to the car boot [trunk]. You put the box in one arm to hold it while you reach inside your pocket for the keys and, you guessed it, the keys are in the other pocket! So you shift the load onto the other arm to get the keys out or you become a contortionist by trying to get it with the opposite arm. So Murphy's Law for keys says that keys are always in the pocket that you can't reach."

Students are then asked to design experiments to test the probability that keys will consistently lodge in the wrong pocket.

Which assumes you are about to eat a piece of toast buttered on one side, when it slips from your grasp and then you learn ...

"The more expensive the carpet the greater the chance that the piece of toast that falls off your plate will land butter side down."

Drawing pins, (I looked this up) are New Zealand English for thumbtacks. These thumbtacks are always slippery, which is how you discover ...

"If a drawing pin drops on the floor the chance of it landing sharp end up increases as its distance to the nearest bare foot decreases."

Which describes an urgent situation where you need to use transparent tape, which they call "cellotape," to quickly repair something. As you grope for the tape with your fingers, you discover that ...

"The more of a rush you are in the harder it is to find the start of a roll of cellotape."

Which transcends national boundaries and says:

"Whatever queue [line] you join, no matter how short it looks, will always take the longest for you to get served."

That's how they teach probability and statistics in New Zealand. Imagine spending a week designing experiments about frustrating supermarket lines, ungraspable tape, foot seeking thumbtacks and carpet soiling toast. You wouldn't want to leave your bed. But somehow, the Education Minister thinks thinking darkly is good preparation for a successful life in the 21st century. Could the Minister possibly know something we don't?

Though maybe this isn't fair. If you looked at my homework assignments in sixth grade, they were all about getting on a train leaving St. Louis at 6 a.m. and heading for Kansas City at 60 miles an hour, while someone else in Chicago at 4 a.m. was also going to Kansas City, but at 75 miles an hour, and I was supposed to figure out who got to Kansas City first. Did knowing who arrives first in Kansas City better prepare me for success in the 20th century? You bet it did! Look at me! I've got my own blog! So we should respect curriculum developers. They can read the future. They know what's coming.

(All illustrations by Robert Krulwich/NPR)

Source: http://www.npr.org/blogs/krulwich/2013/01/24/170083243/wile-e-coyote-teaches-math-and-despair-to-lucky-students-in-new-zealand?ft=1&f=1007

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Netflix comeback? Q4 earnings wow investors.

Netflix?has re-emerged as a stock-market star, netting impressive earnings despite stiff competition from Amazon and Redbox. 2 million new streaming subscribers in the US propelled Netflix to an unexpected fourth-quarter profit.

By Michael Liedtke,?AP Technology writer / January 24, 2013

Netflix customer Carleen Ho holds up movies rented from Netflix, at her home in Palo Alto, Calif. Netflix said Wednesday, Jan. 23, 2013, that its Internet video service added 2 million U.S. subscribers during the final three months of the year to produce an unexpected profit for the company.

Paul Sakuma/AP/File

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Netflix?has re-emerged as a stock-market star after a fourth-quarter performance that demonstrated its success in broadening the appeal of its Internet video service despite stiffer competition.

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The results announced Wednesday served as a resounding endorsement of?Netflix?Inc. CEO Reed Hastings, who has been spending heavily to license more compelling movies and TV shows in hopes of warding off intensifying competitive threats. Companies such as Amazon.com Inc. and Coinstar Inc.'s Redbox have expanded into streaming video to Internet-connected devices to compete with?Netflix.

Hastings' strategy has been met with widespread skepticism, but it paid off during the final three months of last year.

Netflix?gained 2 million video-streaming subscribers in the U.S. during the quarter, propelling the company to a profit during a period that was supposed to produce a loss. In a letter to investors, Hastings credited the gains to people's interest in watching a wide range of entertainment on the tablet computers and Internet-connected TVs that they got as holiday gifts.

"As the sales of tablets go, apparently so go the fortunes of?Netflix," Wedbush Securities analyst Michael Pachter said.

Investors were euphoric.?Netflix's?volatile stock soared $36.24, or more than 35 percent, to $139.50 in extended trading after the numbers came out. If the rally carries over into Thursday's regular trading,?Netflix's?stock would hit a new 52-week high. It would also mark a nearly 80 percent increase since the company's early December announcement of a licensing deal with The Walt Disney Co. for exclusive streaming rights to new movies beginning in 2016.

The upturn in?Netflix's?stock has been a boon for billionaire investor Carl Icahn, who began accumulating a 10 percent stake in the company in early September when the stock was trading below $55.

Despite the recent rebound,?Netflix's?stock remains well below its peak price of nearly $305 reached in July 2011. That was around the same time the company outraged subscribers with a change that increased prices by as much as 60 percent for those who wanted to stream video and still rent DVDs through the mail. Hastings has been scrambling to make amends since the backlash triggered mass cancellations.

"There is still an echo and a bruise," Hastings told analyst during a Wednesday conference call. "We are still extremely thoughtful and careful about what we are trying to do. It wouldn't take much for the issue to flare up again or for us to lose trust. You might say we are on probation at this point, so we are out of jail."

The fourth-quarter surge in new customers left?Netflix?with 27.1 million U.S. subscribers to its streaming service, which costs $8 per month. Hastings said he believes the U.S. streaming service eventually will have 60 million to 90 million subscribers, although he hasn't set a timetable for reaching that goal.

"We have a long way to go, but we are very happy with the quarter," Hastings said in a Wednesday interview.

Netflix's?international expansion also picked up steam as the company ended the quarter with an additional 1.8 million subscribers outside the U.S.

That gave?Netflix?33.3 million video-streaming subscribers worldwide as?Netflix?began the new year, up by nearly 10 million from the start of 2012.

Netflix?also still has 8.2 million customers signed up for the DVD-by-mail rental plans that launched the company's early success. Although?Netflix?is phasing out the disc service, the company hung on to more of the DVD subscribers than it anticipated during the fourth quarter.?Netflix?lost 382,000 DVD subscribers during the quarter.

Netflix?seems confident it will build upon its recent momentum in the current quarter, which will be highlighted by the Feb. 1 debut of a much-anticipated TV series called "House of Cards." The series is produced exclusively for the video streaming service and stars Academy Award-winning actor Kevin Spacey.

In his letter, Hastings described "House of Cards" ''as a defining moment in the development of Internet TV."?Netflix?is releasing all 13 episodes of the first season simultaneously on the hunch that the added convenience will foster more subscriber loyalty instead of encouraging people to sign up for the service for just a month or two to watch exclusive series such as "House of Cards."

The company, which is based in Los Gatos, Calif., forecast that its video streaming service will pick up 1.35 million to 2.1 million in the U.S. during the first three months of this year.

Netflix?also expects to break even or generate another profit during the quarter. Analysts previously thought the company would lose money to start the year as expenses for the international expansion and video-licensing fees outpace revenue growth.

Although he applauded?Netflix's?fourth-quarter performance, Pachter still believes?Netflix's?rising bills to license video will hobble the company.

"I think the company is genuinely mistaken in how it thinks it is going to manage content costs," Pachter said. "This is truly a house of cards and it's going to come crashing down this year."

As of Dec. 31,?Netflix?owed $5.6 billion in licensing fees during the next five years, up from $5 billion through Sept. 30. In an indication that he believes?Netflix?can shoulder the financial load, Hastings told analysts Wednesday that he is interested in licensing Sony Corp.'s' latest movies in a deal similar to the one recently struck with Disney. Sony currently has a licensing agreement with the Starz pay-TV channel that ends in 2015.

Netflix?earned nearly $8 million, or 13 cents per share, in the fourth quarter. That was a 78 percent plunge from net income of $35.2 million, or 64 cents per share, at the same time last year.

Taking their cue from?Netflix's?own projections in October, analysts polled by FactSet had predicted the company's would lose 12 cents per share, also because of expenses for expansion and licensing.

Revenue climbed 8 percent from the previous year to $945 million, about $10 million above expectations.

For the full year, earned $17 million, or 29 cents per share, on revenue of $3.6 billion.?Netflix?had started the year warning it might sustain an annual loss for the first time in a decade. The company earned $226 million, or $4.16 per share, on revenue of $3.2 billion in 2011.

Source: http://rss.csmonitor.com/~r/feeds/csm/~3/p5qAkTrH6NM/Netflix-comeback-Q4-earnings-wow-investors.

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Media Can?t Break Its Wingnut Fever (OliverWillisLikeKryptoniteToStupid)

Share With Friends: Share on FacebookTweet ThisPost to Google-BuzzSend on GmailPost to Linked-InSubscribe to This Feed | Rss To Twitter | Politics - Top Stories Stories, RSS and RSS Feed via Feedzilla.

Source: http://news.feedzilla.com/en_us/stories/politics/top-stories/279115086?client_source=feed&format=rss

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Can Apple's Stock Recover Without Steve Jobs?

Apple's stock is going down like a plane in flames sinking 12 percent on its biggest fall since the 2008 Wall Street crash. That's $60 dollars per share just after they announced one of its best quarters in history... but still under analysts' expectations, who think the company is slowing down because its markets are saturated. The markets they created. More »


Source: http://feeds.gawker.com/~r/gizmodo/full/~3/fa8mfhsnpsI/can-apples-stock-recover-without-steve-jobs

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